Force-feedback joystick as a low-cost haptic interface for an atomic-force-microscopy nanomanipulator |
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Authors: | FJ Rubio-Sierra RW Stark S Thalhammer WM Heckl |
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Institution: | Institut für Kristallographie und Angewandte Mineralogie, Ludwig Maximilians Universit?t München, Theresienstr. 41, 80333 Munich, Germany, DE
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Abstract: | In order to manipulate materials at the nanometer scale, new methods and devices have to be developed. A nanomanipulator interface
was designed and implemented in a commercial atomic-force-microscope (AFM) system. With the aid of a positioning joystick,
direct positioning of the AFM probe with nanometer precision was possible. A commercial force-feedback joystick served as
a haptic interface and provided the user with real-time feeling of the tip–sample interactions. Due to the open design, the
manipulator interface could be used with other microscopes of the SPM family. In addition, the nanomanipulator and an UV-laser
microbeam for photoablation were combined on an inverted optical microscope. To test the nanomanipulator, human metaphase
chromosomes were dissected using both photoablation and mechanical AFM manipulation. The experimental results show that by
combining both methods, biological material can be manipulated on different size scales in one integrated instrument. The
effects of manipulation on the chromosome were studied in detail by AFM. Sub-400 nm cuts were achieved by photonic ablation.
Chromosomal fragments of a size less than of 500 nm could be isolated. By means of mechanical microdissection, different cut
sizes ranging from 80 nm to 500 nm could be easily obtained by applying different load forces.
Received: 2 September 2002 / Accepted: 2 September 2002 / Published online: 5 March 2003
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ID="*"Current affiliation: Nanotechnology Group, ETH Zurich, Switzerland
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ID="**"Corresponding author. Fax: +49-89/2180-4331, E-mail: heckl@lmu.de |
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Keywords: | PACS: 81 16 Rf 87 80 Mj |
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