Kost-Sagitullin Rearrangement and Other Isomerization Recyclizations of Pyrimidines. (Review)

Data on the isomerization recyclizations of pyrimidines, particularly the Kost-Sagitullin and other transformations accompanied by substitution of an endocyclic atom in pyrimidine by an extracyclic nitrogen or carbon atom (N-N, N-C, or C-C recyclizations), are summarized and analyzed. Data from research on the Kost-Sagitullin and certain other isomerization transformations of pyrimidines at the Institute of Organic Chemistry, National Academy of Sciences of the Republic of Armenia, in recent years are presented. In memory of Aleksei Nikolaevich Kost — a distinguished scientist, a warmhearted person, and a teacher. __________ Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1445–1480, October, 2005.