Direct patterning of silanized-biomolecules on semiconductor surfaces |
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Authors: | Nyamjav Dorjderem Holz Richard C |
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Institution: | The Department of Chemistry, Loyola University Chicago, 1068 West Sheridan Road, Chicago, Illinois 60626, United States. |
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Abstract: | A novel approach to pattern silanized-biomolecules directly onto glass (SiO(x)) substrates via Dip-Pen nanolithography (DPN) and microcontact printing (μCP) is presented. Subsequent hybridization reactions of DPN patterned silanized-DNA with its complementary strands provide "proof-of-concept" that the patterned oligonucleotides maintain their biological activities. The fabrication strategy does not require premodification of substrates and offers a cheap and robust way to immobilize molecules on electronically important semiconductor surfaces. |
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