Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC |
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| Authors: | Shirude Pravin S Ying Liming Balasubramanian Shankar |
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| Institution: | Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UKCB2 1EW. |
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| Abstract: | Single molecule fluorescence spectroscopy has been employed to resolve the conformational heterogeneity, hybridization kinetics and study mutational effects on the c-MYC promoter G-quadruplex. |
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