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Different Mechanisms for Nanoparticle Formation between pDNA and siRNA Using Polyrotaxane as the Polycation
Authors:Dr. Yuma Yamada  Masahiro Hashida  Taku Nomura  Prof. Hideyoshi Harashima  Dr. Yuichi Yamasaki  Prof. Kazunori Kataoka  Dr. Atsushi Yamashita  Dr. Ryo Katoono  Prof. Nobuhiko Yui
Affiliation:1. Laboratory for Molecular Design of Pharmaceutics, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita‐12, Nishi‐6, Kita‐ku, Sapporo 060‐0812 (Japan), Fax: (+81)?11‐706‐4879;2. Graduate School of Engineering, The University of Tokyo, Hongo 7‐3‐1, Bunkyo‐ku, Tokyo 113‐8656 (Japan);3. School of Materials Science, Japan Advanced Institute of Science and Technology, 1‐1 Asahidai, Nomi, Ishikawa 923‐1292 (Japan);4. Current address: Institute of Bioengineering and Nanotechnology, 31 Biopolis way, The Nanos, #07‐01, 138‐669 (Singapore);5. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2‐3‐10, Kanda‐Surugadai, Chiyoda Tokyo 101‐0062 (Japan)
Abstract:
Keywords:DNA  nanoparticles  nucleic acids  polymers  RNA
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