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Antibacterial Behavior of Pyridinecarboxylatesilver(I) Complexes
Authors:Romina Abarca  Grace Gomez  Carla Velasquez  Maritza A. Paez  Miguel Gulppi  Abel Arrieta  Manuel I. Azocar
Affiliation:Laboratory of Bioinorganic Chemistry, Faculty of Chemistry and Biology, University of Santiago of Chile, Av. Bernardo O'Higgins 3363, Santiago, Chile
Abstract:FT‐IR spectroscopy of carboxylic groups and viability tests were useful to understand the antibacterial properties of six highly efficient silver(I) pyridinecarboxylate (nicotinic, picolinic and isonicotinic acids) and bipiridinecarboxylate (pyridine‐2,3‐dicarboxylic, pyridine‐2,4‐dicarboxylic and pyridine‐2,5‐dicarboxylic acids) complexes with Ag? O and Ag? N bonds against E. coli (ATCC 25922) and Streptococcus agalactiae (ISP 329‐09). The results show a tendency between the nature of Ag? X (X=oxygen and nitrogen) bonds and the rate or efficiency of antibacterial behavior.
Keywords:silver complexes  antibacterial  Ag?O and Ag?N bonds  FTIR
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