Electrochemistry and Simultaneous Detection of Metabolites of Purine Nucleotide Based on Large Mesoporous Carbon Modified Electrode |
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| Authors: | Lina Liu Huan Wang Xiangjie Bo Li Yang Liping Guo |
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| Institution: | 1. Faculty of Chemistry, Northeast Normal University, Changchun, 130024, P.?R. China tel: +86‐0431‐85099762;2. fax: +86‐0431‐85099762 |
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| Abstract: | A large mesoporous carbon modified glassy carbon electrode (LMC/GCE) was prepared. The morphology and structure of the LMC were characterized. The LMC/GCE was used to investigate the electrochemical behaviors of metabolites of purine nucleotide, uric acid (UA), xanthine (XA) and hypoxanthine (HX). The LMC/GCE exhibited high electrocatalytic activity towards the three compounds when compared with those obtained at the GCE. Furthermore, the LMC/GCE realized simultaneous determination of UA, XA and HX at a physiological pH of 7.0 with wide linear range and low detection limit. The electrocatalytic activity of the LMC/GCE towards guanine (G) and adenine (A) was also investigated. |
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| Keywords: | Metabolites of purine nucleotide Large mesoporous carbon Electrocatalysis Simultaneous detection |
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