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Simple and Efficient Method for Deprotection of Tetrahydropyranyl Ethers by Using Silica Supported Sodium Hydrogen Sulphate
Authors:K. Ravi Kumar  P. V. V. Satyanarayana  B. Srinivasa Reddy
Affiliation:1. RA Chem Pharma Limited, Research and Development Division, Prasanth Nagar, Hyderabad 500072, AP, India;2. Department of Chemistry, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur, 522510, AP, India
Abstract:Tetrahydropyranyl (THP) ethers have been efficiently and simply deprotected by using Silica supported sodium hydrogen sulphate (NaHSO4‐SiO2) in methanol at room temperature to regenerate the parent alcohols in high yields.
Keywords:THP ethers  deprotection  NaHSO4‐SiO2  methanol  reusable catalyst
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