Reactions of N-substituted 3-azabicyclo[3.3.1]nonan-9-ones with N,N-, N,S-, and N,O-binucleophiles |
| |
Authors: | A I Moskalenko V I Boev |
| |
Institution: | (1) Lipetsk State Pedagogical University, ul. Lenina 42, Lipetsk, 398020, Russia |
| |
Abstract: | Condensation of N-substituted 3-azabicyclo3.3.1]nonan-9-ones with difunctional N,N-, N,S-, and N,O-centered nucleophiles (o-phenylenediamine, 1,2-diphenylethane-1,2-diamine, 2-aminobenzenethiol, cysteine, 2-aminophenol, serine) gave the corresponding spiro heterocyclic compounds fused at the C9 atom. Treatment of N-tert-butoxycarbonyl-substituted spiro compounds with anhydrous hydrogen chloride resulted in elimination of the tert-butoxycarbonyl group with formation of spiro3-azabicyclo3.3.1]nonane-9,2′-azole] hydrochlorides. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|