Synthesis, Characterization, and Biological Activity of n -Tributyltin Derivatives of Pharmaceutically Active Carboxylates |
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| Authors: | Saira Shahzadi Moazzam H. Bhatti Khadija Shahid Saqib Ali Saadia R. Tariq Mohammad Mazhar Khalid M. Khan |
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| Affiliation: | (1) College of Horticulture and Landscape Architecture, Southwest University, 400715 Chongqing, China;(2) Department of Oncology, The Ninth People’s Hospital of Chongqing, 400700 Chongqing, China;(3) College of Pharmaceutical Sciences, Southwest University, 400715 Chongqing, China;(4) Department of Chemistry, Changwon National University, 641-773 Changwon, South Korea; |
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| Abstract: | Tributyltin(IV) derivatives of six different pharmaceutically active carboxylates were synthesized. The complexes were characterized by different analytical techniques (elemental analysis; infrared, NMR, and mass spectroscopy). 119Sn NMR data were also recorded in six different coordinating and non-coordinating solvents. The antibacterial activities of the compounds were tested using ten different bacteria relative to the reference drugs ampicillin and cephalexin. |
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