| γ-聚谷氨酸水凝胶的性质、制备及其应用 |
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| 引用本文： | 庄华红 王淑芳*高靖辰 洪彦航 高伟霞 宋存江. γ-聚谷氨酸水凝胶的性质、制备及其应用[J]. 应用化学, 2014, 31(3): 245-255. DOI: 10.3724/SP.J.1095.2014.30172 |
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| 作者姓名： | 庄华红 王淑芳*高靖辰 洪彦航 高伟霞 宋存江 |
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| 作者单位： | (南开大学生命科学学院1.生物活性材料教育部重点实验室；2.分子微生物与技术教育部重点实验室 天津 300071) |
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| 基金项目： | 国家“973”计划(2012CB725204),国家自然科学基金资助项目(51073081,31070039)，天津市自然科学基金资助项目(13JCYBJC24900) |
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| 摘 要： | 系统介绍了γ-聚谷氨酸水凝胶的制备方法及其生物可降解性、高吸水性及保湿性、pH敏感性、生物相容性和可修饰性等性能，同时综合介绍了其在组织工程、药物控释和创面修复等方面的应用，结合本研究组工作对其未来的发展进行了展望。
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| 关 键 词： | &gamma -聚谷氨酸 同聚物 水凝胶 制备 |
| 收稿时间： | 2013-04-10 |
| 修稿时间： | 2013-06-07 |
Preparation,Performances and Application of γ-Polyglutamic Acid Hydrogel |
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| ZHUANG Huahong,WANG Shufang,GAO Jingchen,HONG Yanhang,GAO Weixia,SONG Cunjiang. Preparation,Performances and Application of γ-Polyglutamic Acid Hydrogel[J]. Chinese Journal of Applied Chemistry, 2014, 31(3): 245-255. DOI: 10.3724/SP.J.1095.2014.30172 |
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| Authors: | ZHUANG Huahong WANG Shufang GAO Jingchen HONG Yanhang GAO Weixia SONG Cunjiang |
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| Affiliation: | (1.Education Ministry Key Laboratory of Bioactive Materials;2.Education Ministry Key Laboratory of Molecular Microbiology and Technology,College of Life Science,Nankai University,Tianjin 300071,China) |
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| Abstract: | Preparation and performances of γ-polyglutamic acid(γ-PGA) hydrogel were introduced systematically in this paper, including biodegradability, high water absorption and moisture retention, pH sensitivity, biocompatibility and modifiability. A comprehensive review of γ-PGA hydrogel in tissue engineering, drug delivery, wound healing and other applications was given. In addition, combined with the work of the authors, the future development of γ-PGA hydrogel was prospected. |
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| Keywords: | γ-polyglutamic acid homopolymer hydrogel preparation |
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