Research in the imidazole series |
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Authors: | A. A. Druzhinina P. M. Kochergin |
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Affiliation: | (1) S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, USSR;(2) All-Union Scientific-Research Institute of the Technology of Blood Substitutes and Hormonal Preparations, Moscow |
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Abstract: | The hydrolysis of 7-cyano derivatives of pyrrolo[1,2-a]imidazole in 85–90% sulfuric acid at 100°C gives amides of pyrroloimidazole-7-carboxylic acids. Under more severe conditions, the resulting carboxylic acids are decarboxylated to the corresponding pyrroloimidazole derivatives with a free 7 position.See [1] for communication XC.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1658–1659, December, 1976. |
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