Studies on cardiotonic agents. II. Synthesis of novel phthalazine and 1,2,3-benzotriazine derivatives |
| |
| Authors: | Y Nomoto H Obase H Takai M Teranishi J Nakamura K Kubo |
| |
| Institution: | Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd., Japan. |
| |
| Abstract: | A series of phthalazine and 1,2,3-benzotriazine derivatives which have heterocyclylpiperidino groups was synthesized and tested for cardiotonic activity in anesthetized dogs. Several 6,7-dimethoxyphthalazine derivatives showed relatively potent cardiotonic activity comparable to that of amrinone. |
| |
| Keywords: | |
|
|
