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A highly efficient protocol for the synthesis of N-aryl nucleobases using zinc oxide in ionic liquids |
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| Authors: | A Zare A Hasaninejad A Khalafi-Nezhad A R Moosavi-Zare M H Beyzavi F Khedri F Asadi N Hayati A Asifi |
| Institution: | 1. Department of Chemistry, Payame Noor University (PNU), Iran 2. Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr, 75169, Iran 3. Department of Chemistry, College of Sciences, Shiraz University, Shiraz, 71454, Iran |
| Abstract: | A highly efficient and simple method for the synthesis of N-aryl derivatives of pyrimidine and purine nucleobases via Narylation of nucleobases using zinc oxide in 1-butyl-3-methylimidazolium bromide (bmim]Br) under microwave as well as thermal conditions is described. In both conditions, the title compounds were produced in high to excellent yields and in short reaction times. |
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