An efficient and rapid synthetic route to biologically interesting pyranochalcone natural products |
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| Authors: | Lee Yong Rok Wang Xue Xia Likai |
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| Institution: | School of Chemical Engineering and Technology, Yeungnam University, Gyeongsan 712-749, Korea. yrlee@yu.ac.kr |
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| Abstract: | An efficient and concise total synthesis of naturally occurring pyranochalcones was achieved from readily available 2,4-dihydroxyacetophenone and 2,4-dihydroxy-6-methoxyacetophenone. The key steps in the synthetic strategy were ethylenediamine diacetate-catalyzed benzopyran formation and aldol reactions. |
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