Synthesis of the tetrahydroisoquinoline alkaloid (+/-)-renieramycin G and A (+/-)-lemonomycinone analogue from a common intermediate |
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| Authors: | Magnus Philip Matthews Kenneth S |
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| Affiliation: | Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712. |
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| Abstract: | ![]()
The total synthesis of tetrahydroisoquinoline alkaloids (+/-)-renieramycin G (4) and a lemonomycinone analogue (7) is described. A general strategy to synthesize both the mono- and bistetrahydroisoquinoline alkaloids from a common advanced intermediate, 17, is presented. |
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