基于点击化学和活性自由基聚合方法制备双重响应金纳米粒子

采用点击化学和可逆加成断裂链转移活性自由基聚合方法制备了温度和pH双重响应的金纳米粒子. 通过红外光谱(FTIR)、X射线光电子能谱(XPS)、透射电子显微镜(TEM)及热重分析(TGA)等方法对双重响应性金纳米粒子进行了表征. 该金纳米杂化粒子具有良好的分散性, 其表面接枝聚合物的密度约为0.6 Chain/nm2. 通过改变温度和pH条件, 考察了金纳米杂化粒子的可逆响应行为. 实验结果表明, 点击化学和可逆加成断裂链转移活性自由基聚合方法实现了金纳米粒子修饰的简单化、可控化以及功能化.

Preparation of Dual Responsive Gold Nanoparticles Using Click Chemistry and Living Radical Polymerization

A novel simple and efficient route was carried out for preparation of dual responsive gold nanoparticles based on click chemistry and reversible addition-fragmentation chain transfer(RAFT) polymerization. The functionalized hybrid gold nanoparticles were characterized by FTIR, XPS, TEM and TGA methods. The results indicate that the hybrid gold nanoparticles are dispersed well. The surface grafting density of hybrid nanoparticles are calculated to be about 0.6 Chains/nm2. In addition, the hybrid gold nanoparticles show dual responsive phenomenon as the temperature or pH value changed. It is demonstrated that the route of preparation of hybrid gold nanoparticles was simplified controlled and functionalized using click chemistry/RAFT polymerization method.