| Epoxide Hydrolase-catalyzed Resolution of Ethyl 3-Phenylglycidate |
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| 引用本文： | CongFaLI QiaoLIU HongJieCUI DiDING AiGuoJI YinBoQU. Epoxide Hydrolase-catalyzed Resolution of Ethyl 3-Phenylglycidate[J]. 中国化学快报, 2003, 14(11): 1133-1134 |
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| 作者姓名： | CongFaLI QiaoLIU HongJieCUI DiDING AiGuoJI YinBoQU |
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| 作者单位： | [1]StateKeyLaboratorvofMicrobialTechnology.ShandoneUniversity.Jinan250100 [2]CollegeofPharmacy,ShandongUniversity,Jinan250012 |
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| 基金项目： | 国家自然科学基金，国家自然科学基金 |
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| 摘 要： | Epoxide hydrolase-catalyzed resolution of ethyl 3-phenylglydidate was investigated using resting cells ofPseudomonas sp. BZS21. Under the present conditions 26.2 % of (2R, 3S)-ethyl 3-phenylglycidate with ee value of 94.6 % was obtained from the racemic mixture.
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| 关 键 词： | 环氧水解酶 催化剂 乙基3-苯基甘油酯 不对称水解 假单胞菌 氨基肽酶 中间体 抗癌活性 |
Epoxide Hydrolase-catalyzed Resolution of Ethyl 3-Phenylglycidate |
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| Cong Fa LI,Qiao LIU,Hong Jie CUI,Di DING,Ai Guo JI,Yin Bo QU. Epoxide Hydrolase-catalyzed Resolution of Ethyl 3-Phenylglycidate[J]. Chinese Chemical Letters, 2003, 14(11): 1133-1134 |
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| Authors: | Cong Fa LI Qiao LIU Hong Jie CUI Di DING Ai Guo JI Yin Bo QU |
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| Abstract: | Epoxide hydrolase-catalyzed resolution of ethyl 3-phenylglydidate was investigated using resting cells of Pseudomonas sp. BZS21. Under the present conditions 26.2 % of (2R, 3S)- ethyl 3-phenylglycidate with ee value of 94.6 % was obtained from the racemic mixture. |
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| Keywords: | Epoxide hydrolase ethyl 3-phenylglycidate resolution asymmetric hydrolysis. |
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