A facile and highly efficient route to alpha-amino phosphonates via three-component reactions catalyzed by Mg(ClO4)2 or molecular iodine |
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Authors: | Wu Jie Sun Wei Xia Hong-Guang Sun Xiaoyu |
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Institution: | Department of Chemistry, Fudan University, Shanghai, China. jie_wu@fudan.edu.cn |
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Abstract: | Three-component reactions of aldehydes, amines, and diethyl phosphite catalyzed by Mg(ClO4)2 or molecular iodine afforded the corresponding alpha-amino phosphonates in excellent yields under mild reaction conditions. |
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