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A facile and highly efficient route to alpha-amino phosphonates via three-component reactions catalyzed by Mg(ClO4)2 or molecular iodine
Authors:Wu Jie  Sun Wei  Xia Hong-Guang  Sun Xiaoyu
Institution:Department of Chemistry, Fudan University, Shanghai, China. jie_wu@fudan.edu.cn
Abstract:Three-component reactions of aldehydes, amines, and diethyl phosphite catalyzed by Mg(ClO4)2 or molecular iodine afforded the corresponding alpha-amino phosphonates in excellent yields under mild reaction conditions.
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