Electrochemical behavior of thiamine on a self-assembled gold electrode and its square-wave voltammetric determination in pharmaceutical preparations. |
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| Authors: | Qijin Wan Nianjun Yang Yongkang Ye |
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| Institution: | Department of Chemistry, Hubei Normal University, Huangshi, P R China. qijinwan@hs.hb.cninfo.net |
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| Abstract: | The electrochemical behavior of thiamine on a self-assembled electrode of L-cysteine (Cys/SAM/Au) has been investigated and Cys/SAM/Au can be used to detect thiamine using square-wave voltammetry (SWV). At pH 11.40 Britton-Robinson buffer, thiamine exhibits a well-defined anodic peak on Cys/SAM/Au. Under the optimized conditions, the anodic peak current of SWV was linear with the content of thiamine in the range of 1.1 x 10(-8) - 2.2 x 10(-6) mol/L; the detection limit was 5.5 x 10(-9) mol/L. The method was successfully applied to the determination of thiamine in pharmaceutical preparations. |
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