Prediction of coating uniformity in batch fluidized-bed coating process |
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| Institution: | 1. School of Mechanical Engineering, The University of Newcastle, Callaghan 2308, Australia;2. School of Chemical Engineering, The University of Queensland, St Lucia 4072, Australia;3. Centre for Bulk Solids and Particulate Technologies, Newcastle Institute for Energy and Resources, The University of Newcastle, Callaghan 2308, Australia;1. College of Mechanical and Electronic Engineering, Shandong University of Science and Technology, Qingdao 266590, China;2. Shandong Province Key Laboratory of Mine Mechanical Engineering, Shandong University of Science and Technology, Qingdao 266590, China;3. School of Information Science and Engineering, Shandong Normal University, Jinan 250014, China;4. School of Mechanical Engineering, North China University of Water Resources and Electric Power, Zhengzhou 450045, China;1. College of Chemical Engineering, Hebei University of Technology, Tianjin 300401, China;2. Qingdao Institue of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, Shandong, China;3. Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China;1. Dalian National Laboratory for Clean Energy, National Engineering Laboratory for MTO, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China;2. State Key Laboratory of Heavy Oil Processing, China University of Petroleum, Beijing 102249, China;1. Department of Chemical and Process Engineering, University of Surrey, Guildford GU2 7XH, United Kingdom;2. Department of Mechanical Engineering, University of Johannesburg, South Africa;3. Research Center Pharmaceutical Engineering GmbH, Graz 8010, Austria;1. School of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China;2. Multiphase Flow Systems, Institute of Process Engineering, Otto-von-Guericke-University Magdeburg, Hoher Weg 7b, D-06120 Halle (Saale), Germany |
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| Abstract: | Coating of particulate materials in fluidized beds is a widely used technique to eliminate particle agglomeration, provide slow release of an active substance, or protect active ingredients. When thin polymer shells are applied on a particle surface, it is important to determine the process parameters that provide coating uniformity. In this study, the degree of coverage, defined as the fraction of the coated surface of the particles, is proposed as a quantitative criterion of coating uniformity. A new model for the batch fluidized-bed coating process is presented. The model allows prediction of the function of particle distribution according to the degree of coverage at a given process time and thereby enables assessment of coating uniformity. An algorithm for the numerical solution of model equations for a batch fluidized-bed coater is described. The influences of the main process parameters on the coating uniformity were shown. |
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| Keywords: | Coating uniformity Degree of coverage Encapsulation Fluidized-bed coating Mathematical modeling |
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