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Quinazolines. 4*. Acylation of quinazoline-2,4-diones with aromatic acids chlorides in the presence of ferric chloride hexahydrate
Authors:R. Sh. Kuryazov  Yu. R. Takhirov  D. A. Dushamov  N. S. Mukhamedov  K. K. Turgunov  Kh. M. Shakhidoyatov  B. Tashkhodjaev
Affiliation:(1) S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, Tashkent, 100170, Uzbekistan;
Abstract:The interaction of quinazoline-2,4-diones with aromatic acids chlorides in nitrobenzene has been investigated in the presence of FeCl3·6H2O. Optimum conditions for the acylation reaction have been developed, the used 4-substituted benzoyl chlorides have been put in order of relative activity, depending on the degree of their electrophilicity.
Keywords:
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