Quinazolines. 4*. Acylation of quinazoline-2,4-diones with aromatic acids chlorides in the presence of ferric chloride hexahydrate |
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Authors: | R. Sh. Kuryazov Yu. R. Takhirov D. A. Dushamov N. S. Mukhamedov K. K. Turgunov Kh. M. Shakhidoyatov B. Tashkhodjaev |
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Affiliation: | (1) S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, Tashkent, 100170, Uzbekistan; |
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Abstract: | The interaction of quinazoline-2,4-diones with aromatic acids chlorides in nitrobenzene has been investigated in the presence of FeCl3·6H2O. Optimum conditions for the acylation reaction have been developed, the used 4-substituted benzoyl chlorides have been put in order of relative activity, depending on the degree of their electrophilicity. |
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