| Investigation of the interaction of DNA and neutral red by?uorescence spectroscopic analysis |
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| 作者姓名： | Yong Nian Ni a b Xue Zhi Zhong a a |
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| 作者单位： | Yong Nian Ni a，b，Xue Zhi Zhong a a Department of Chemistry，Nanchang University，Nanchang 330047，China b The Key Laboratory of Food Science of MOE，Nanchang University，Nanchang 330047，China |
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| 摘 要： | The binding characteristics of neutral red (NR) with DNA were investigated by fluorescence spectrometry. Chemometrics approach as singular value decomposition (SVD) was used to evaluate the number of spectral species in the drug-DNA binding process, and then the intrinsic binding constant of 1.6 104 in base pairs and the binding site number of 0.97 were obtained from the Scatchard plot.
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Investigation of the interaction of DNA and neutral red by?uorescence spectroscopic analysis |
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| Yong Nian Ni a,b,Xue Zhi Zhong a a.Investigation of the interaction of DNA and neutral red by?uorescence spectroscopic analysis[J].Chinese Chemical Letters,2007(5). |
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| Authors: | Yong Nian Ni a b Xue Zhi Zhong a a |
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| Institution: | Yong Nian Ni a,b,Xue Zhi Zhong a a Department of Chemistry,Nanchang University,Nanchang 330047,China b The Key Laboratory of Food Science of MOE,Nanchang University,Nanchang 330047,China |
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| Abstract: | |
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| Keywords: | Neutral red DNA Binding constant Fluorescence Chemometrics Singular value decomposition |
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