Characterization and Aggregation Behaviors of Mixed DDAB/SDS Solution With and Without Poly(4-styrenesulfonic Acid-Co-Maleic Acid) Sodium |
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| Authors: | Feifei Li Xiaoli Liu Jianmei Pang Guimei Lin Wei Shao |
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| Affiliation: | 1. School of Pharmaceutical Science and Center for Pharmaceutical Research &2. Drug Delivery Systems , Shandong University , Jinan, Shandong Province, P. R. China |
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| Abstract: | Synthetic vesicles are formed by cationic and anionic surfactants, didodecyldimethylammonium bromide (DDAB), and sodium dodecylsulfate (SDS). The morphology, size, and aqueous properties of cationic/anionic mixtures are investigated at various molar ratios between cationic and anionic surfactants. The charged vesicular dispersions made of DDAB/SDS are contacted or mixed with negatively charged polyelectrolyte, poly(4-styrenesulfonic acid-co-maleic acid) sodium (PSSAMA), to form complexes. Depending on DDAB/SDS molar ratio or PSSAMA/vesicle charge ratio, complexes flocculation or precipitation occur. Characterization of the cationic/anionic vesicles or complexes formed by the catanionic vesicles and polyelectrolytes is performed by transmission electron microscope (TEM), dynamic light scattering (DLS), conductivity, turbidity, and zeta potential measurements. The size, stability, and the surface charge on the mixed cationic/anionic vesicles or complexes are determined. |
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| Keywords: | Catanionic vesicle complexes didodecyldimethylammonium bromide (DDAB) polyelectrolyte sodium dodecylsulfate (SDS) |
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