One Convenient Preparation and Characterization of a New Amphiphilic Cationic Cyclodextrin Derivative 2-O-(Hydroxypropyl-N,N-Dimethyl-N-Dodecylammonio)-β-Cyclodextrin |
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| Authors: | Hong Yuan Sun Yan Bai Shan Jian Cao Jian Shen |
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| Affiliation: | 1. School of Chemistry and Chemical Engineering, Shandong University , Jinan, P.R. China;2. Key Laboratory of Colloid and Interface Chemistry, Shandong University, Ministry of Education , Jinan, P.R. China |
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| Abstract: | A new amphiphilic cyclodextrin derivative 2-O-(hydroxypropyl-N,N-dimethyl-N-dodecylammonio)-β-cyclodextrin (2-HPDMDA-β-CD) was prepared and characterized by surface tension, electrical conductivity, dynamic light scattering, transmission electron microscopy (TEM) and steady-state fluorescence. 2-HPDMDA-β-CD was found to be a fine surfactant with a smaller critical micelle concentration (1.21 mM) value than that of dodecyltrimethylammonium chloride. TEM showed that 2-HPDMDA-β-CD could form two kinds of spherical aggregates in solution. The smaller one showed little concentration dependence while the larger one showed relatively strong concentration dependence. 2-HPDMDA-β-CD could be a fine host compound in molecular recognition with two functional spaces of the cyclodextrin cavity and micelles. |
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| Keywords: | Amphiphilic cyclodextrin derivative functional spaces surfactants |
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