New Values of the Required Hydrophilic-Lipophilic Balance for Oil in Water Emulsions of Solid Fatty Acids and Alcohols Obtained from Solubility Parameter and Dielectric Constant Values |
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| Authors: | Ricardo C. Pasquali Carlos Bregni Melina P. Taurozzi |
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| Affiliation: | 1. Departamento de Tecnología Farmacéutica , Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires , Buenos Aires, Argentina rcpasquali@yahoo.com;3. Departamento de Tecnología Farmacéutica , Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires , Buenos Aires, Argentina |
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| Abstract: | The goals of this articles are to find a correlation between the required HLB values and the solubility parameters of oils; find a more precise correlation between the required HLB values and the dielectric constant, than the one obtained by other authors; and to determine the required HLB values for o/w emulsions of solid fatty acids and alcohols from the values of the solubility parameters and dielectric constants, that could be more trustful than the ones obtained by the methodology proposed by Griffin. It was obtained lineal relation between required HLB and solubility parameter (r = 0.995). Also it was observed lineal relations between required HLB and dielectric constants or logarithm of the dielectric constant more precise than the one obtained by other authors. |
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| Keywords: | Dielectric constant fatty acids fatty alcohol required HLB solubility parameter |
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