Substituent-dependent fluorescent sensors for zinc ions based on carboxamidoquinoline |
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Authors: | Yu Zhang Xiangfeng Guo Lihua Jia Shicheng Xu Zhihui Xu Libo Zheng Xuhong Qian |
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Affiliation: | College of Heilongjiang Province Key Laboratory of Fine Chemicals, Qiqihar University, Qiqihar, 161006, China. xfguo@163.com. |
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Abstract: | A series of carboxamidoquinoline-based fluorescent sensors (the AQZ family) were synthesized and characterized. The AQZ family members were highly soluble in water and showed good selectivity for Zn(2+)via enhanced fluorescence in aqueous buffer solution. Fluorescence signals could be tuned from dual-wavelength ratiometric changes to changes in the intensity of a single wavelength upon binding Zn(2+) through the introduction of different substituents onto the quinoline ring. Concentrations of free Zn(2+) of 10(-5)-10(-6) M could be detected using the sensors. Changes of substituents and their positions on the quinoline ring influenced the sensitivity for Zn(2+), but had little effect on Zn(2+) affinities. |
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