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Supramolecular Peptide Amphiphile Vesicles through Host-Guest Complexation |
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| Authors: | Dezhi Jiao Jin Geng Xian Jun Loh Debapratim Das Tung-Chun Lee Oren A Scherman |
| Institution: | Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW (UK). |
| Abstract: | Tricky triggering: Supramolecular peptide amphiphiles were prepared by host-guest complexation of pyrene-labeled peptides and viologen lipid with cucurbit8]uril. They self-assemble into vesicles, which are responsive to a variety of external triggers. Both "switching on" and "switching off" of fluoresence and cytotoxicity is demonstrated in?vitro. |
| Keywords: | cucurbit[8]uril fluorescence sensing host–guest complexes living cell imaging peptide amphiphiles |
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