|
|||||
|
|
| 1,2-二甲基咪唑啉的合成及表征 | |
| 引用本文： | 徐文清,聂万丽,Borzov Maxim V.,马兵锋.1,2-二甲基咪唑啉的合成及表征[J].有机化学,2009,29(5):802-805. |
| 作者姓名： | 徐文清 聂万丽 Borzov Maxim V. 马兵锋 |
| 作者单位： | 1. 西北大学化学系,西安,710069 2. 西北大学化学系,西安,710069;国立莫斯科大学化学系,莫斯科,119992 3. 国立莫斯科大学化学系,莫斯科,119992 |
| 基金项目： | 国家自然科学基金，陕西省外国专家局引进国外技术管理人才项目 |
| 摘 要： | 对1,2-二甲基咪唑啉的合成进行了详细研究. 以甲胺水溶液和2-溴乙胺氢溴酸盐(1)为原料进行反应, 在两种原料物质的量之比为5∶1, 缓缓回流12 h的条件下, 得到N-甲基乙二胺(2), N-甲基乙二胺经过乙酸化得到N-甲基-N,N′-二乙酰基乙二胺(3), 然后, N-甲基-N,N′-二乙酰基乙二胺和氧化钙在高温下关环得到1,2-二甲基咪唑啉(4). 并对所得到的产物1,2-二甲基咪唑啉经元素分析, 1H NMR, IR和GC-MS得到了表征. |
| 关 键 词： | N-甲基-N N′-二乙酰基乙二胺 成环反应 1 2-二甲基咪唑啉 水解 |
| 收稿时间： | 2008-7-2 |
| 修稿时间： | 2008-10-23 |
Synthesis and Charaterization of 1,2-Dimethylimidazoline |
|
| Xu,Wenqing,Nie,Wanli,Borzov Maxim V.,Ma,Bingfeng.Synthesis and Charaterization of 1,2-Dimethylimidazoline[J].Chinese Journal of Organic Chemistry,2009,29(5):802-805. | |
| Authors: | Xu Wenqing Nie Wanli Borzov Maxim V Ma Bingfeng |
| Institution: | (a Department of Chemistry, Northwest University, Xi’an 710069) (b Department of Chemistry, Moscow State University, Moscow 119992) |
| Abstract: | Here a convenient and comparatively cheap route to DMI was provided, which includes that (a) N-methyl ethylenediamine (2) was prepared from aqueous methylamine solution and 1-amino-2-bromo- ethane hydrobromide (1) (molar ratio 5∶1) under gentle reflux during 12 h, (b) N-methyl- N,N′-diace- tylethylenediamine (3) was obtained via direct acetulation of 2 with acetic acid, and (c) the target molecule 1,2-dimethylimidazoline (4) was prepared by CaO catalyzed cyclization of 3 at elevated temperature. All compounds were characterized by elemental analysis, 1H NMR, IR and GC-MS techniques. |
| Keywords: | N-methyl-N N′-diacetylethylenediamine cyclization 1 2-dimethylimidazoline hydrolysis |
| 本文献已被 维普 万方数据 等数据库收录！ | |
| 点击此处可从《有机化学》浏览原始摘要信息 | |
| 点击此处可从《有机化学》下载免费的PDF全文 | |