Cytotoxic iridoid aldehydes from Taiwanese Viburnum luzonicum |
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| Authors: | Fukuyama Yoshiyasu Minoshima Yuka Kishimoto Yoshiko Chen Ih-Sheng Takahashi Hironobu Esumi Tomoyuki |
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| Institution: | Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan. fukuyama@ph.bunri-u.ac.jp |
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| Abstract: | Four new iridoid aldehydes bearing (E)- or (Z)-p-coumaroyl group, luzonial A (1), luzonial B (2), luzonidial A (3), and luzonidial B (4), were isolated from a methanol extract of the dried leaves of Viburnum luzonicum collected in Kaoshiung, Taiwan and their structures were elucidated by analysis of spectroscopic data. Compounds 1-3 exhibited moderate inhibitory activity against HeLa S3 cancer cells. |
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