Enantioselective synthesis of bicyclo[2.2.2]octenones using a copper-mediated oxidative dearomatization/[4 + 2] dimerization cascade |
| |
| Authors: | Dong Suwei Zhu Jianglong Porco John A |
| |
| Affiliation: | Department of Chemistry and Center for Chemical Methodology and Library Development (CMLD-BU), Boston University, Boston, Massachusetts 02215, USA. |
| |
| Abstract: | An enantioselective approach to bicyclo[2.2.2]octenone structures utilizing a copper-mediated asymmetric oxidative dearomatization/[4 + 2] dimerization cascade is described. The total synthesis and absolute stereochemistry reassignment of (+)-aquaticol has been achieved using the methodology. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
