New samarium(III) complex of 5‐aminoorotic acid with antioxidant activity |
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| Authors: | Irena Kostova Maria Valcheva‐Traykova |
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| Institution: | 1. Department of Chemistry, Faculty of Pharmacy, Medical University, Sofia, Bulgaria;2. Department of Medical Physics and Biophysics, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria |
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| Abstract: | A samarium(III) complex (SmAOA) of 5‐aminoorotic acid (HAOA) was synthesized by reaction of the respective inorganic salt and ligand in a molar ratio of 1:3. The structure of the complex was determined by means of elemental analysis and UV–visible, NMR, Fourier transform infrared (FT‐IR) and FT Raman spectroscopies. Significant differences in the FT‐IR and FT Raman spectra of the complex were observed as compared to the spectra of the free ligand. Detailed vibrational analysis of HAOA and Sm(III)–AOA systems revealed that the binding mode in the complex was bidentate through the carboxylic oxygen atoms. The newly synthesized SmAOA showed antioxidant properties. The antioxidant activities of both HAOA and SmAOA were related to their electron donor properties. Copyright © 2015 John Wiley & Sons, Ltd. |
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| Keywords: | Sm(III) complex 5‐aminoorotic acid IR Raman NMR antioxidant activity |
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