Simultaneous measurements of diffusion and transverse relaxation in exercising skeletal muscle |
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| Affiliation: | 1. Department of Biophysics, University Paris V-COCHIN, 75014 Paris, France;2. Service Hospitalier Frédéric Joliot, C.E.A., 91406 Orsay, France;1. Department of Electrical Devices and High Voltage Technology, Lublin University of Technology, 20-618 Lublin, Poland;2. Belarusian State University, 220030 Minsk, Belarus;3. Research Institute for Nuclear Problems of Belarusian State University, 220030 Minsk, Belarus;1. Key Laboratory of Ecosystem Network Observation and Modelling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China;2. College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100190, China;3. Key Laboratory of Watershed Geographic Sciences, Nanjing Institute of Geography Limnology, Chinese Academy of Sciences, Nanjing 210008, China |
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| Abstract: | The aim of this study was to compare proton T2 and apparent diffusion coefficient (ADC) variations induced by exercise in skeletal muscle, to provide some more information on the source of their variations. T2 and ADC were measured in the forearm flexor digitorum muscles in 12 healthy volunteers at rest and after an exercise, using a sequence allowing simultaneous measurements of both parameters. At rest, T2 was 30.6 ± 1.8 ms (mean ± 1 SD) and ADC was 1.82 ± 0.11 × 10−9 m2/s. With exercise, T2 varied by +28 ± 12% (p < .001 vs. rest) and ADC varied by +12 ± 3% (p < .001). The recovery of T2 after exercise was faster than that of ADC, with half-times of 7 ± 2 min and of 15 ± 8 min (p < .01), respectively. It is concluded that both T2 and ADC increase with exercise. However, the mechanisms of variation of T2 and ADC with exercise are probably different, T2 mostly reflecting changes in water content and ADC reflecting temperature variations. |
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