Activation of area V5 by visual perception of motion demonstrated with echoplanar MR imaging |
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| Affiliation: | 1. Department of Radiology, the Second Affiliated Hospital, Zhejiang University School of Medicine, No.88 Jiefang Road, Shangcheng District, Hangzhou 31009, China;2. Department of Neurology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China;3. School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China;4. School of Information Science and Technology, ShanghaiTech University, Shanghai, China;5. Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, United States;6. Helen Wills Neuroscience Institute, University of California, Berkeley, CA, United States;1. Department of Radiation Biology and Radiotherapy, College of Medicine of the University of Lagos, Lagos, Nigeria;2. Department of Biomedical Engineering, Faculty of Basic Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria;3. Department of Anatomy, Faculty of Basic Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria;4. Department of Morbid Anatomy, Faculty of Basic Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria;5. Department of Anesthesia, Faculty of Clinical Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria |
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| Abstract: | Cortical activation in visual association areas known to be responsible for the perception of motion was investigated in two volunteers who viewed a projected animated cartoon periodically “run” and “frozen” during collection of echoplanar MR images. Ten axial, contiguous, 5 mm thick, T2-weighted, gradient-echo images (TE 40 ms, TR 3000 ms) depicting BOLD contrast were acquired through the occipital lobe using a GE Signa 1.5 T system with an advanced NMR operating console. Images were analysed by time series regression modelling estimating power in the MR signal at the ON-OFF frequency of motion. Highly significant activation in response to motion perception was identified in both subjects bilaterally in area V5. |
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