Reconstituted olfactory receptors in bilayer lipid membranes |
| |
| Affiliation: | 1. School of Computing, Engineering & Mathematics, University of Western Sydney, Australia;2. School of Engineering and Information Technology, the University of New South Wales, Canberra, Australia;3. Department of Civil Engineering, Dhaka University of Engineering & Technology (DUET), Bangladesh |
| |
| Abstract: | Bullfrog olfactory receptors were reconstituted in bilayer lipid membranes (BLMs). Three odorants were presented to the reconstituted system. The three structurally related odorants were diethylsulfide (DES), thiophene (THP) and diethanolsulfide (DOS). The ordorants were presented in pairs. DOS induced a response in the presence of either of the other two odorants. DES and THP did not induce a response in the presence of either of the other two odorants. These observations suggest that there are two substructures, one common to the three odorants and one that is unique to DOS. The results support the notion that olfactory receptors detect certain molecular segments of odorants. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
