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纳米材料在肿瘤光动力治疗中的研究进展
引用本文:张远东,张 卓,董紫薇,阚君满. 纳米材料在肿瘤光动力治疗中的研究进展[J]. 化学通报, 2023, 86(2): 173-178
作者姓名:张远东  张 卓  董紫薇  阚君满
作者单位:吉林工商学院 科研处,吉林工商学院 科研处,吉林工商学院 粮食学院,吉林工商学院 科研处
基金项目:吉林省教育厅项目(JJKH20220210KJ)和吉林工商学院科研项目(KB2021[003])资助
摘    要:光动力治疗是新兴的非侵入性癌症治疗方法。纳米材料以其独特的结构以及光物理、光化学性质成为可用于光动力治疗的光敏剂。根据纳米材料的不同种类,分别对无机非金属纳米材料、无机金属纳米材料、有机小分子纳米材料以及有机聚合物纳米材料等的构建策略及其在光动力治疗肿瘤中的应用进行综述。展望了纳米材料在未来肿瘤光动力治疗中的挑战和发展方向。为新一代纳米光敏剂的构建提供创新思路,并扩展其在癌症治疗中的潜力。

关 键 词:肿瘤  光动力治疗  纳米材料
收稿时间:2022-07-05
修稿时间:2022-09-04

Progress in Nanomaterials for Tumor Photodynamic Therapy
ZHANG Yuan-dong,ZHANG zhuo,DONG zi-wei and KAN Jun-man. Progress in Nanomaterials for Tumor Photodynamic Therapy[J]. Chemistry, 2023, 86(2): 173-178
Authors:ZHANG Yuan-dong  ZHANG zhuo  DONG zi-wei  KAN Jun-man
Affiliation:Department of Scientific Research,Jilin Business and Technology College,Department of Scientific Research,Jilin Business and Technology College,School of Grain Science and Technology,Jilin Business and Technology College,Department of Scientific Research,Jilin Business and Technology College
Abstract:Photodynamic therapy has emerged as an innovative non-invasive treatment for cancer. Nanomaterialswith distinctive structure, photophysical and photochemical properties have been utilized as photosensitizer forphotodynamic therapy of tumors. The construction strategies of nanomaterials and their applications in photodynamictherapy are reviewed according to the different categories of nanomaterials, such as inorganic non-metallicnanomaterials, inorganic metallic nanomaterials, organic small molecule nanomaterials, and organic polymericnanomaterials. The future challenges and development directions of the nanomaterials in photodynamic therapy areprospected. It is expected that this paper will provide innovative ideas for constructing a new generation ofnanophotosensitizers and expand their potential applications in cancer treatment.
Keywords:photodynamic  therapy, nanomaterials, tumor
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