Kadsuphilactones A and B, two new triterpene dilactones from kadsuraphilippinensis |
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| Authors: | Shen Ya-Ching Lin Yu-Chi Chiang Michael Y Yeh Sheau Farn Cheng Yuan-Bin Liao Chia-Ching |
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| Affiliation: | Department of Marine Resources, National Sun Yat-Sen University, Taiwan, Republic of China. ycshen@mail.nsysu.edu.tw |
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| Abstract: | [structure: see text]. Two novel triterpene dilactones, kadsuphilactones A (1) and B (2), were isolated from the Taiwanese medicinal plant Kadsura philippinensis. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic methods, including two-dimensional NMR techniques, and confirmed by X-ray crystallographic analysis. Kadsuphilactone B (2) exhibited in vitro anti-HBV activity with IC(50) values of 6 microg/mL by HBsAg enzyme immunoassay. |
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