Continuous fermentation for the production of citric acid from glucose |
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Authors: | Klasson T K Clausen E C Gaddy J L |
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Institution: | 1.Department of Chemical Engineering, University of Arkansas, 72701, Fayetteville, AR ; |
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Abstract: | Citric acid is finding new areas of use each year and the demand for the acid is constantly increasing. Being a bulk chemical,
the continuous production of citric acid would be advantageous. The paper presents the results from ammonia limited batch
and continuous fermentations using the yeast strainSaccharomycopsis (Candida) lipolytica (NRRL Y-7576). Mathematical models were developed for growth and glucose utilization in batch and continuous culture. Cell
and acid yields appeared to be almost the same in batch and continuous culture. The specific production rates were found to
be constant, equal to 0.053 g/g h, in the batch fermentations but varied in the continuous experiments from 0 to 0.11 g/g
h depending on the fermentation conditions. Continuous production in a single stage CSTR was studied for over 1,000 hours
without shutdown. |
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Keywords: | Index Entries" target="_blank">Index Entries Citric acid Saccharomycopsis lipolytica Candida lipolytica continuous production stirred-tank reactor |
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