Cobalt(II) complexes of 5,7-dimethyl[1,2,4]-triazolo-[1,5-a]-pyrimidine. Spectroscopic characterization,XRD study and antimicrobial activity |
| |
| Authors: | María A Romero Juan M Salas Miguel Quirós David J Williams José Molina |
| |
| Institution: | (1) Departamento de Química Inorgánica, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain;(2) Department of Chemistry, Imperial College of Science, Medicine and Technology, SW7 2AY London, UK;(3) Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain |
| |
| Abstract: | Summary Several cobalt(II) complexes of 5,7-dimethyl-1,2,4]-tria-zolo-1,5-a]-pyrimidine (DMTP) have been prepared and characterized by thermal and spectroscopic techniques. The crystal structure of Co(DMTP)2(H2O)4]Br2·2H2O has been determined by XRD; the metal ion is octahedrally coordinated by two DMTP ligands through the usual N(3) site and four water molecules. Metal binding to N(3) for DMTP is consistent with the electronic properties calculated with the MOPAC programme. All the complexes were screened for their activity against several types of bacteria, showing a broad-spectrum antimicrobial activity. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
