The synthesis of some phenothiazinyl ketones and their derivatives

The synthesis of a number of 2-chloro-8-acylphenothiazines via the Friedel-Crafts reaction has been reported. A series of dialkylaminoalkyl ketones have been derived from 2-chloroacetyl- and 2-chloro-8-chloroacetylphenothiazines. A number of dialkylaminoalkyl esters of 2-phenothiazinecarboxylic acid have also been synthesized.