Application of HPLC column-switching in pesticide residue analysis |
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Authors: | E A Hogendoorn C E Goewie and P van Zoonen |
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Institution: | (1) National Institute of Public Health and Environmental Protection, P.O. Box 1, NL-3720 BA Bilthoven, The Netherlands;(2) Present address: DHV Raadgevend Ingenieursbureau BV, P.O. Box 85, NL-3800 AB Amersfoort, The Netherlands |
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Abstract: | Summary An overview is given of the applicability of HPLC with column-switching in pesticide residue analysis. The main advantage of HPLC with column-switching is the enhancement of both sensitivity and selectivity combined with a high potential for automation. The selection of optimal conditions such as column dimensions, mobile phase compositions and multi step gradient elution is discussed. |
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