| DNA Binding and Cleavage Property of Pyrenyl-macrocyclic Polyamine Conjugate |
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| 引用本文： | Qiang YIN Zhen ZHANG Yu Fen ZHAO. DNA Binding and Cleavage Property of Pyrenyl-macrocyclic Polyamine Conjugate[J]. 中国化学快报, 2006, 17(9): 1185-1188 |
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| 作者姓名： | Qiang YIN Zhen ZHANG Yu Fen ZHAO |
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| 作者单位： | The Key Laboratory of Bioorganic Phosphorus Chemistry ＆ Chemical Biology （Ministry of Education）, Department of Chemistry, Tsinghua University, Beijing 100084 |
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| 基金项目： | 国家自然科学基金;科技部-教育部-清华大学合作项目 |
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| 摘 要： | In the past few years, there have been intensive investigations on artificial nuclease since they play a great role as a molecular tool in biochemistry1-9. Classical artificial nuclease includes two parts: DNA binding unit and chemically reactive moiety. …
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| 关 键 词： | DNA分裂 ESI-MS UV 琼脂糖凝胶电泳 芘基大环聚胺共轭物 |
| 收稿时间： | 2006-03-27 |
DNA Binding and Cleavage Property of Pyrenyl-macrocyclic Polyamine Conjugate |
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| Qiang YIN,Zhen ZHANG,Yu Fen ZHAO. DNA Binding and Cleavage Property of Pyrenyl-macrocyclic Polyamine Conjugate[J]. Chinese Chemical Letters, 2006, 17(9): 1185-1188 |
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| Authors: | Qiang YIN Zhen ZHANG Yu Fen ZHAO |
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| Affiliation: | Ministry of Education |
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| Abstract: | We reported the synthesis of a simple bifunctional molecule and the interaction between this molecule and DNA were studied by UV and the DNA cleavage behavoior was determined by agarose gel electrophoresis. |
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| Keywords: | DNA cleavage ESI-MS UV agarose gel electrophoresis. |
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