Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein |
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| Authors: | Reetz Manfred T Peyralans Jérôme J-P Maichele Andrea Fu Yu Maywald Matthias |
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| Affiliation: | Max-Planck-Institut für Kohlenforschung, D-45470 Mülheim/Ruhr, Germany. reetz@mpi-muelheim.mpg.de |
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| Abstract: | The concept of utilizing the methods of directed evolution for tuning the enantioselectivity of synthetic achiral metal-ligand centers anchored to proteins has been implemented experimentally for the first time. |
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