| 合成生物学展望 |
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| 引用本文： | 贾斌,李炳志,元英进. 合成生物学展望[J]. 中国科学:化学, 2014, 0(9): 1455-1460 |
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| 作者姓名： | 贾斌 李炳志 元英进 |
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| 作者单位： | 天津大学系统生物工程教育部重点实验室天津化学化工协同创新中心合成生物学研究平台,天津300072 |
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| 基金项目： | 国家自然科学基金（21390203）;国家重点基础研究发展计划（2014CB745100）;国家高技术研究发展计划（2012AA02A701）资助 |
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| 摘 要： | 近年来,合成生物学快速发展成为一个新兴交叉学科领域,研究重点逐渐由基因线路、简单元件和模块的设计构建转向设计与构建复杂的人工生物系统.本文阐述了合成生物学与化学工程学科的内在联系,并从基因组的人工设计合成与编辑、人工细胞的设计合成、人工合成多细胞体系及其应用等方面展望了未来合成生物学的发展趋势.
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| 关 键 词： | 合成生物学 化学工程 基因组编辑 人工合成基因组 人工合成细胞 人工多细胞体系 |
Prospects of synthetic biology |
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| JIA Bin,LI BingZhi,YUAN YingJin. Prospects of synthetic biology[J]. Scientia Sinica Chimica, 2014, 0(9): 1455-1460 |
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| Authors: | JIA Bin LI BingZhi YUAN YingJin |
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| Affiliation: | ( Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300072, China) |
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| Abstract: | Synthetic biology has developed into a new engineering discipline with multidisciplinary features. In addition to the design and construction of genetic parts and circuits, the new developmental phase of synthetic biology focuses more on the construction of complex artificial biosystems. We firstly review the relationship between synthetic biology and chemical engineering. Subsequently, we review the future trend of synthetic biology, including artificial synthesis and editing of genome, design and construction of designer cells, and synthetic microbial consortia. |
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| Keywords: | synthetic biology chemical engineering genome editing synthetic genome designer cell artificial microbial consortia |
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