Fluorescence Properties of Selected Benzo[c]phenanthridines |
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Authors: | Kamil Motyka Jakub Stýskala Petr Canka? Jan Hlavá? |
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Institution: | 1. Department of Organic Chemistry, Faculty of Science, Institute of Molecular and Translational Medicine, Palacky University, 17. Listopadu 12, 771 46, Olomouc, Czech Republic
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Abstract: | The fluorescence properties of selected benzoc]phenanthridines (BPs) were examined. The effect of structure, pH and solvent on the fluorescence properties has been investigated. It was found out that the presence of charged iminium nitrogen significantly decreased the fluorescence of the compounds. The fluorescence (intensity as well as emission spectra shape) of the investigated compounds was significantly dependent on pH as well as used solvent. The utilization in epigenetic modification mechanisms studies as demethylase probe and as possible pH indicator was suggested. |
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