Practical and Green Protocol for the Synthesis of Substituted 4H‐Chromenes Using Room Temperature Ionic Liquid Choline Chloride–Urea |
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| Authors: | C. N. Revanna T. R. Swaroop G. M. Raghavendra D. G. Bhadregowda K. Mantelingu K. S. Rangappa |
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| Affiliation: | Department of Studies in Chemistry, University of Mysore, , Manasagangothri, Mysore, 570006 India |
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| Abstract: | An efficient and convenient synthesis of substituted 4H‐chromenes is described using room temperature ionic liquid (RTIL) choline chloride–urea in one pot under solvent free conditions. Three‐component Knoevenagel condensation of an aromatic aldehyde, with an active methylene compound, and a cyclohexane dione is reported. This new approach has advantage of excellent yields (82–96%), clean reaction, and short reaction time (15–30 min) at room temperature. |
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