Microwave‐Assisted Solvent‐Free Synthesis of Highly Functionalized Pyrimidine Derivatives |
| |
| Authors: | Shengjiao Yan Yanfei Niu Xuebing Chen Yongjiang Liu Jun Lin |
| |
| Institution: | Key Laboratory of Medicinal Chemistry for Natural Resources (Yunnan University), Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, People's Republic of China |
| |
| Abstract: | We here described an efficient method for the synthesis of a series of highly functionalized pyrimidines via the addition and condensation reaction of ketene dithioacetals with guanidine carbonate or amidine hydrochlorides by microwave irradiation under solvent‐free conditions in the absence of a catalyst, giving the products with good yields (79–98%). |
| |
| Keywords: | |
|
|
