Two New 4‐Hydroxyisoflavanes from the Root of Codonopsis cordifolioidea and Their Anti‐virus Activities |
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| Authors: | Xuemei Gao Huaixue Mu Xuesen Li Guangyu Yang Ganpeng Li Qiufen Hu |
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| Affiliation: | 1. Key Laboratory of Ethnic Medicine Resource Chemistry (Yunnan University of Nationalities), State Ethnic Affairs Commission & Ministry of Education, Kunming 650031, P. R. China;2. Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P. R. China |
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| Abstract: | Two new 4‐hydroxyisoflavanes, cordifoliflavanes A and B (1 and 2), were isolated from the roots of Codonopsis cordifolioidea. Their structures were elucidated by spectroscopic methods, including extensive 1D‐ and 2D‐NMR techniques. Compounds 1 and 2 were tested for their anti‐HIV‐1 activities and anti‐tobacco mosaic virus activities. The results showed that compounds 1 and 2 have modest anti‐HIV‐1 activities and anti‐tobacco mosaic virus activities, respectively. |
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| Keywords: | 4‐Hydroxyisoflavane Codonopsis cordifolioidea Anti‐HIV‐1 activities Anti‐tobacco mosaic virus |
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