Synthesis and X‐ray characterization of 2,5,6‐trisubstituted imidazo[2,1‐b][1,3,4]thiadiazole derivatives |
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Authors: | Yu‐Xia Da Ji‐Hua Zhu Zhang Zhang Xiao‐Dong Jia Cai‐Xia Yang Zheng‐Jun Quan |
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Institution: | 1. Key Laboratory of Eco‐Environment‐Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, Gansu 730070, People's Republic of China;2. Gansu Key Laboratory of Polymer Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, Gansu 730070, People's Republic of China |
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Abstract: | A series of 2,5,6‐trisubstituted imidazo2,1‐b]1,3,4]thiadiazoles via Mannich reaction of imidazo2,1‐b]1,3,4]thiadiazoles with morpholine and formaldehyde were synthesized. Structures of all the newly synthesized compounds are well supported by spectral data such as IR, NMR, Mass, and Elemental analysis. Compound 3a has been confirmed by X‐ray diffraction studies. J. Heterocyclic Chem., (2012). |
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