Three‐Component Domino Reaction in PPG: An Easy Access to 4‐Thiazolidinone Derivatives |
| |
| Authors: | Davinder Prasad Mahendra Nath |
| |
| Institution: | Department of Chemistry, University of Delhi, , Delhi, 110007 India |
| |
| Abstract: | A simple, economical, and convenient synthesis of a new series of 4‐thiazolidinone derivatives using one‐pot three‐component condensation of aromatic amines, thioglycolic acid and aromatic aldehydes or cyclohexanone in polypropylene glycol (PPG), a recyclable and inexpensive solvent medium is reported. All the reactions are carried out at 110°C without using catalyst or additives. The products are obtained in good to excellent yields (60–97%) after easy workup and purification. |
| |
| Keywords: | |
|
|
